ABOUT OFF-X

Unexpected toxicity and safety issues constitute one of the most disruptive events in drug R&D, with one third of drug attrition still directly related to these events. In this context, a translational approach to drug safety and prompt access to actionable safety intelligence can significantly reduce patient burden and avoid costly failures.

Since 2017, the Clarivate OFF-X^TM portal has been supporting translational researchers in pharmaceutical and healthcare organizations to de-risk drug R&D programs.

By delivering critical integrated preclinical toxicity and clinical adverse event intelligence coupled to advanced analytics, Clarivate OFF-X^TM allows safety liabilities to be monitored and anticipated across all phases of drug R&D and post-marketing

Rapid access to actionable safety intelligence via OFF-X provides a critical competitive advantage for your R&D:

Time saving: OFF-X reduces the time and resources required to retrieve critical safety intelligence. OFF-X breaks information silos by comprehensively integrating disparate sources of data with a fast turnaround.
Comprehensiveness: OFF-X’s extensive coverage of information sources provides daily access to key data that is not readily available and that may not be published elsewhere after a first mention, for example a reference in a scientific congress.
OFF-X covers all phases of drug R&D, including first-in-class and emerging targets.
OFF-X provides a unique translational approach: used across a wide range of departments and facilitates the translational safety intelligence paradigm by interconnecting and integrating critical safety intelligence form early target discovery to post-marketing and patient safety.

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